Overview
Acute epiglottitis is the inflammation of the epiglottitis, typically caused by the bacteria Haemophilus influenzae type B (Hib). Although it is rare due to Hib vaccination, it is an airway emergency and can be life-threatening.
Epidemiology
- Due to immunisation to Hib, acute epiglottitis is extremely rare
- Usually presents at around 2-5 years in children and 40-50 years in adults
Risk Factors
- No previous Hib vaccine
- Immunocompromised state
Presentation
Epiglottitis presents as a severe and acute onset of:
- Sore throat and high fever
- Muffled voice
- Drooling
- Stridor
- ‘Tripod position’ – the patient finds it easier to breathe sitting leaning forward with the next extended
- This may manifest in younger children as them wanting to sit upright instead of lying down
- ‘Toxic appearance’ – lethargy, poor perfusion, cyanosis, inconsolably irritable
Do not examine the airway or do anything that may agitate the child (e.g. separating them from a parent), as this may precipitate the closure of the airway.
Investigations
Overview
Do not examine the airway or do anything that may agitate the child (e.g. separating them from a parent), as this may precipitate the closure of the airway.
The diagnosis of epiglottitis is only made in a controlled operating theatre setting with senior/airway-trained staff. Investigations involve:
- Laryngoscopy
- An x-ray may be considered:
- Posteroanterior view: subglottic narrowing (steeple sign)
- Lateral view: swelling of the epiglottis (thumb sign)
Differential Diagnoses
Inhaled foreign body
- Symptoms such as cough present more suddenly
- Auscultation shows focal wheezing
- No fever or prodrome of symptoms of a viral illness
Peritonsillar abscess
- Dysphagia, drooling, occasional stridor, neck stiffness
- Unilateral cervical lymphadenopathy
- The uvula may deviate away from the affected side
Tonsillitis
- Red tonsils with or without tonsillar exudate
- Stridor, drooling, and ‘tripod’ position are less likely to be present
Croup
- Barking cough present
- Drooling, and ‘tripod’ position are less likely to be present unless croup is severe
Management
Overview
- Immediately alert a senior paediatrician and anaesthetist
- Secure the airway – endotracheal intubation may be necessary
- IV antibiotics and corticosteroids may be used
Complications
- Death
- Abscess formation
- Pneumonia
- Meningitis
- Sepsis
- Mediastinitis
Prognosis
- Most patients recover without requiring intubation
- Earlier identification and treatment result in a good prognosis with a quick and complete recovery